Now, MIT researchers have developed a new technique that more than doubles the usual depth limit of metabolic imaging. Their method also boosts imaging speeds, yielding richer and more detailed images. This new technique does not require tissue to be preprocessed, such as by cutting it or staining it with dyes. Instead, a specialized laser illuminates deep into the tissue, causing certain intrinsic molecules within the cells and tissues to emit light. This eliminates the need to alter the tissue, providing a more natural and accurate representation of its structure and function. The researchers achieved this by adaptively customizing the laser light for deep tissues. Using a recently developed fiber shaper ' a device they control by bending it ' they can tune the color and pulses of light to minimize scattering and maximize the signal as the light travels deeper into the tissue. This allows them to see much further into living tissue and capture clearer images. Greater penetration...
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